one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the procedure of various myeloma. Its synthesis or analyze is very important for guaranteeing the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound within the synthesis of imatinib, a drug that targets unique sorts of cancer, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers for instance breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their research is vital for optimizing the production system and making certain large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilised to take care of breast Fulvestrant Intermediates-5 cancer, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist used in the procedure of breast cancer. Several intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers including ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the treatment of colorectal cancer and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have different apps, together with antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of CAS NO. 122111-01-7 vildagliptin, an oral drug for type 2 diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of assorted gluconic acid derivatives, which are Employed in food, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication made use of to deal with form two diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).